Mentor: Dr. Karyn Esser
College of Medicine
"Research always rang synonymous with behind-the-scenes work to me. Work that would pay off by advancing or improvement the material or concept studied even by a little. Even though I did not know what research I was interested in, as soon as I started searching, I knew I had found it."
- circadian rhythm in muscules
- anatomy and physiology
- University Scholars Program(2017)
UF ELI Conversation Partners
- UF Shands Volunteer
- Gator Aide Volunteer
Hobbies and Interests
Skeletal muscle circadian rhythms in health and disease
"Circadian rhythms are 24hr oscillations and are regulated by a molecular mechanism, molecular clock, found in every cell. These molecular clocks regulate the cell’s function and research has shown that disruption of the molecular clock is associated with diminished cell function. Therefore, if a muscle cell molecular clock is affected by an illness like cancer, then the skeletal muscle function will be disrupted and this is maybe associated with the significant health problems with cancer.
Dr. Karyn Esser’s lab is testing the impact of chronic disease, such as cancer, on the function of the molecular clocks in skeletal muscle in mice. Data from healthy and diseased circadian reporter mice will be obtained from skeletal muscle, liver and lung. Circadian clock function for each tissue will be obtained through real time bioluminescence assays for each tissue over a 4-day period. My project will be to take the raw data from the bioluminescence assays and use circadian software, called MetaCycle, to analyze the molecular clock’s period length, amplitude, stability, and phase progressions.".