Kyla Rakoczy

 
Mentor: Dr. Elisabeth Barton
Human Health and Performance
 
"I am an APK pre med student with a business minor and believe that seeking research experience in a field within my college is a great way to improve lab skills and make contributions to medical advancements."

Major

Applied Physiology and Kinesiology

Minor

Business

Research Interests

  • Muscular Dystrophy
  • Athletic Injury
  • Cardiovascular Health

Academic Awards

  • Emerging Scholars Program 2015-2016
  • Oneblood Donor Scholar
  • Brown Memorial Scholar
  • Palm Beach Scholar Athlete
  • University Scholars Program 2015

Organizations

  • HHP Ambassadors

Volunteer

  • Shands Hospital volunteer
  • Children's Museum of Boca
  • Metropolitan Ministries

Hobbies and Interests

  • Playing and Watching Sports
  • Lifting Weights
  • Cooking
  • Boating

Research Description

Therapeutic Potential of MAP Kinase Pathway Modulation for LGMD 2C
The research focuses on the gamma-sracoglycan complex and its effects on Limb Girdle and Duchenne muscular dystrophy. Absence of this complex has revealed severe muscle deterioration aberrant signaling which likely contributes to muscular diseases. By isolating one of these aberrant signaling pathways we can see if it’ll have therapeutic effects on Limb Girdle. .We propose to determine that using pharmacological inhibition of ERK1/2 phosphorylation will allow us to understand the potential therapeutic effects on mouse models. We treat young and old mice to see changes in muscle disease progression and reversal, respectively. Aberrant signaling may be a shared consequence of many muscular dystrophies which may expand the benefit of finding its therapeutic effects beyond the scope of only one neuromuscular disease.