Development of a Computational Phantom for Proton Therapy Applications from a Physical Proton Tissue-Equivalent Model

Julia Withrow

Authors:  Julia Withrow, Camilo Correa, Wesley E. Bolch

Faculty Mentor:  Wesley Bolch

College:  Herbert Wertheim College of Engineering


In this project, a virtual model based on CT images of a physical proton tissue-equivalent anthropomorphic phantom is presented. This computational model will be used as a physical phantom surrogate in Monte Carlo (MC) simulations of radiation treatment in Proton Therapy. In previous work, a 10-year-old physical model of proton tissue-equivalent material was constructed. Based on CT imagery of the model, segmentation of the skeleton, lungs, airways and outer-body contours was performed in 3D-Slicer. Segmented objects were then exported as polygon meshes, which then were checked for self-intersections, mesh-mesh intersections and normal vector directions using SpaceClaim. In order to assess organ doses when performing MC simulations with the model created, 10 reference organs were inserted within the computational model created using the software Rhino. For each of the organs inserted, aforementioned intersections were checked and fixed. The model was then converted into a tetrahedral mesh model for future MC applications. This model created is an accurate computed version of the physical proton tissue-equivalent anthropomorphic phantom. Future MC simulations will be conducted using this virtual model to assess out-of-field organ and point doses and compare with the out-of-field doses obtained from proton irradiations of the physical phantom.

Poster Pitch

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Maddie Rodriguez
Maddie Rodriguez (@guest_1978)
1 year ago

Hey Julia! This is awesome. Great job!

Julia Withrow
Julia Withrow (@guest_3750)
Reply to  Maddie Rodriguez
1 year ago

Thank you Maddie, I appreciate it!

Nicole Sarna
Nicole Sarna (@guest_3006)
1 year ago

This is super interesting, awesome job! 🙂

Julia Withrow
Julia Withrow (@guest_3848)
Reply to  Nicole Sarna
1 year ago

Thank you Nicole!

Macartney Ewing
Macartney Ewing (@guest_3942)
1 year ago

Hey Julia! Awesome poster and great visuals! Out of curiosity, what is the difference between the polygon meshes and tetrahedral meshes?

Julia Withrow
Julia Withrow (@guest_5046)
Reply to  Macartney Ewing
1 year ago

Hi Macartney! Thank you. The polygon mesh is just a surface model, while the tetrahedral mesh fills in the model internally with the pyramid-like structures used in place of just triangles. This allows for testing of dosimetry to be faster when running simulations as well.