Professor, Department of Psychiatry, McKnight Brain Institute

Barry Setlow, PhD

Research Website

Dr. Barry Setlow is a Professor in the Departments of Psychiatry, Neuroscience, and Psychology. He is also a member of the Executive Committee for the University of Florida Center for Addiction Research and Education. Much of the research in Dr. Setlow’s laboratory concerns interactions between cognition, motivation, and addiction.  

Dr. Setlow has mentored four University Scholar Students and has published papers including over 25 undergraduates (See list below).  He has also partnered with CUR to recruit students, using our student opportunity database, for a project called Behavioral and neurobiological research on cognition and decision making in the context of aging and substance use. 

Thank you for your contribution to undergraduate Research! 

Publications Featuring Undergraduates

Names marked with a double asterisk (**) are undergraduate students.

Mitchell, M. R.*, Weiss, V. G.**, Beas, B. S.*, Morgan, D., Bizon, J. L., &Setlow, B. (2014). Adolescent risk taking, cocaine self-administration, and striatal dopamine signaling. Neuropsychopharmacology. 39, 955-962. 

Orsini, C. A.†,Ginton, G.**, Shimp, K. G.*, Avena, N. M., Gold, M. S., & Setlow, B. (2014). Food consumption and weight gain after cessation of chronic amphetamine administration. Appetite.78, 76-80. 

Mitchell, M. R.*, Weiss, V. G.**, Ouimet, D. J., Fuchs, R. A., Morgan, D. &Setlow, B. (2014). Intake-dependent effects of cocaine self-administration on impulsive choice in a delay discounting task. Behavioral Neuroscience. 128, 419-429. 

Orsini, C. A.†, Trotta, R.**, Bizon, J. L., &Setlow, B. (2015) Dissociable roles for the basolateral amygdala and orbitofrontal cortex in decision-making under risk of punishment. The Journal of Neuroscience. 35, 1368-1379. 

Orsini, C. A.†, Gilbert, R. J., Willis, M.**, Bizon, J. L., &Setlow, B. (2016)Sex differences in a rat model of risky decision making. Behavioral Neuroscience. 130, 50-61. 

McQuail, J. A.†, Beas, B. S.*, Kelly, K. B.*, Simpson, K. L.**, Frazier, C. J., Setlow, B., & Bizon, J. L. (2016). NR2A-containing NMDARs in the PFC are required for working memory and associated with age-related cognitive decline. The Journal of Neuroscience. 36, 12537-12548. 

Orsini, C. A.†, Mitchell, M. R.*, Shimp, K. G.*, Spurrell, M. S.**, Heshmati, S. C., Bizon, J. L., &Setlow, B.  (2017). Effects of nucleus accumbens amphetamine administration on performance in a delay discounting task. Behavioural Brain Research. 321, 130-136. 

Hernandez, C. M.*, Vetere, L. M.**, Orsini, C. A.†,McQuail, J. A.†, Maurer, A. P., Burke, S. N., Setlow, B., & Bizon, J. L. (2017). Decline of prefrontal cortical-mediated executive functions but attenuated delay discounting in aged Fischer 344 x Brown Norway hybrid rats. Neurobiology of Aging. 60, 141-152. 

Hernandez, C. M.*,McQuail, J. A.†, Schwabe, M. R.**, Burke, S. N., Setlow, B., & Bizon, J. L. (2018). Age-related declines in prefrontal cortical expression of metabotropic glutamate receptors that support working memory. eNeuro. May/June 2018, 5(3) e0164-18.2018 1–17. 

Orsini, C. A.†, Heshmati, S. C., Garman, T. S.**, Wall, S. C., Bizon, J. L., &Setlow, B. (2018). Contributions of medial prefrontal cortex to decision making involving risk of punishment. Neuropharmacology. 205-216. 

Blaes, S. L.*, Orsini, C. A.†, Mitchell, M. R.*, Spurrell, M. S.**,Betzhold, S. M.**, Vera, K.**, Bizon, J. L., & Setlow, B. (2018). Monoaminergic modulation of decision making under risk of punishment. Behavioural Pharmacology. 29, 745-761. 

Blaes, S. L.*, Orsini, C. A.†, Holik, H. M.**, Stubbs, T. D.**, Ferguson, S. N.**, Heshmati, S. C., Bruner, M. M., Wall, S. C., Febo, M.,Bruijnzeel, A. W., Bizon, J. L., & Setlow, B. (2019). Enhancing effects of acute exposure to cannabis smoke on working memory performance. Neurobiology of Learning and Memory. 157, 151-162. 

Hernandez, C. M.*, Orsini, C. A.†,Labiste, C. C., Wheeler, A-R.**, Ten Eyck, T. W.**, Bruner, M. M., Sahagian, T. J.*, Harden, S. W.†, Frazier, C. J., Setlow, B., & Bizon, J. L. (2019). Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats. eLife. 8:e46174. 

Orsini, C. A.†, Blaes, S. L.*, Hernandez, C. M.†,Betzhold, S. M., Perera, H.**, Wheeler, A-R.**, Ten Eyck, T. W.**, Garman, T. S.**, Bizon, J. L., &Setlow, B. (in press). Regulation of risky decision making by gonadal hormones in males and females. Neuropsychopharmacology. 

Hernandez, C. M.*, Orsini, C. A.†, Wheeler, A-R.**, Ten Eyck, T. W.**,Betzhold, S. M.,Labiste, C. C.**, Wright N. G.**, Setlow, B., & Bizon, J. L. (2020). Testicular hormones mediate robust sex differences in intertemporal choice in rats. eLife. 9:e58604.