Current methods for monitoring oxalate kidney stones disease are complex, labor intensive, and require a colorspectrophotometer or ion chromatograph found only in laboratory settings. With 6-12% of the world’s population (including the USA) suffering from kidney stones, together with the rapidly increasing numbers of individuals being identified with hyperoxaluria as a potential cause in a variety of disease as autism and inflammatory bowel disease, the need for regular monitoring of oxalate levels seems vital. Current practice does not make urinary oxalate measurements a cost-effective and timely procedure, generally resulting in such testing performed once post-symptomatic. Thus, the overall goal of this project is to develop a simple, rapid, inexpensive and user-friendly point-of-care monitoring device for measuring oxalate levels in biological fluids on an “as-need-to-know” basis.
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