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Project Title
Function of virus-derived noncoding RNAs in virus infection and tumor development
Time Commitment
11-15 hours/week
Method
Depends on lab funding
Possible Co-Authorship
Yes
Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) are highly ubiquitous human pathogens that are associated with the development of numerous types of tumors. We use a genetically related mouse virus, MHV68, to determine how these types of viruses are able to evade the immune response, establish lifelong infection, and cause tumors. In particular, we are focused on defining the molecular and immunological function of virus-derived noncoding RNAs in these processes. In addition, we use novel genomics platforms to discover new noncoding RNAs.
Email: stibbe@ufl.edu
Phone: (352)-273-5628