Annika Petersen

Student NameAnnika Petersen
Faculty Mentor NameLoic Deleyrolle
CollegeCollege of Medicine
Research InterestsCancer Therapeutics and Host Response, Metastasis
Academic AwardsUniversity Scholars Program 2020
OrganizationsFlorida Club Gymnastics, UF Shoes for Smiles
Hobbies and InterestsGymnastics, guitar

Research Project

Slow cycling cell RNA based T cell therapy to prevent recurrence in glioblastoma (GBM)

The overall objective of this project is to develop a novel targeted immunotherapy strategy based on the use of immunogenic antigens (RNA) isolated from GBM slow-cycling cells as activator of immune effectors in the context of adoptive cell therapy to prevent recurrence in GBM. The specific goals of the project will be to validate the pool of RNA used to prime dendritic cells and generate treatment resistant tumor cells that will be used to assess the antitumor effect of engineered T cell products.