Jake LeClaire

Jake LeClaire


Dr. Elias Sayour


UF Health Cancer Center


Microbiology and Spanish




JHealth, Alpha Epsilon Delta

Academic Awards

UF CLAS Dean's List


Equal Access Clinic Network HOQI

Research Interests

Nanotechnology in Neuro-Oncology, Intracranial Tumors, Tumor Virology and Virus-Host Interaction, Oncolytic Viral Vectors, Anti-Tumor Vaccines, Targeted Cell Therapy

Hobbies and Interests

Soccer, Tennis, Pickleball, Spanish Language and Culture, Music, Reading

Research Project

Development of a novel RNA-Nanoparticle vaccine for cancer immunotherapy

Our laboratory has developed a novel RNA-Nanoparticle (RNA-NP) vaccine against cancer that generates a strong innate immune activation through type 1 interferons that result in adaptive anti-tumor immunity; however, the exact mechanism of action is unclear and anti-tumor efficacy needs to be improved. The goals of this project are to elucidate the molecular mechanism of innate immune activation of our vaccine as well as to modify the RNA design and payload to improve anti-tumor efficacy.