Even though chronic pain affects individuals of all races, ages and genders, members of certain population groups are disproportionately affected, with chronic pain particularly seen as being more prevalent and disabling in older adults. Brain alterations are potential contributors to increased pain in older individuals. Conditioned pain modulation (CPM) is a behavioral paradigm reflective of pain inhibition that is predictive of chronic pain susceptibility in younger cohorts and worse CPM (i.e., less pain inhibition) has been documented in older individuals. This research seeks to understand the associations between brain volume and cortical thickness, and CPM in older adults. Understanding this relationship will help understand the neurobiological mechanisms underlying deficient pain modulation in aging, and pave the way to identify therapeutic targets to reduce chronic pain in the elderly population.