The COVID-19 (Coronavirus disease 2019) is a highly infectious disease that as of January 2021 has resulted in >106 million infections and over 2.3 million deaths worldwide. The rate of transmission of the virus has facilitated the need for “stay-at-home” orders and social distancing recommendations across the world. Consequently, the COVID-19 outbreak severely impacted the process and methodology of in-person behavioral research interventions, which have been impeded due to the added safety concerns of participants. Participant engagement is also likely to be impacted by the mental health outcomes induced by economic recession, terrorism, natural disasters, healthcare insecurities, and other factors that have accompanied this pandemic. The majority of current data and guidelines on behavioral interventions date back to pre-COVID-19 and might not be generalizable for this ‘new normal’ of behavioral interventions. My project aims to identify how the pandemic has affected the participants’ adherence to behavioral intervention recommendations and develop methods to deliver interventions remotely or safely in-person. Clinical and translational researchers may utilize and expand on these findings to help recalibrate methods used in their studies to conduct future behavioral interventions more efficiently in the midst of a public health crisis.