Deep Brain Stimulation (DBS) is a neuromodular therapy proven effective in the treatment of essential tremor (ET) and Parkinson’s patients. Our team uses biophysical modeling techniques to analyze the treatment’s electrophysical effects on neural fibers – and the corresponding Volume of Tissue Activated (VTA) – in the effort to further current research understanding of this treatment method. Additionally, our team investigates the effects of non-conventional DBS settings, such as voltage pulse and frequency variation, so that current DBS patients may have their treatment modified and improved for more effective results.