Hannah Gracy

Hannah Gracy

The association between cognitive function and sleep among people living with HIV in Florida


Hannah Gracy, Shannan Rich, Dr. Vaughn Bryant, Dr. Angel Algarin, Dr. Ronald Cohen, Dr. Robert Cook


Dr. Robert Cook


College of Public Health and Health Professions


Prior research has established that cognitive dysfunction and poor sleep are common among people living with HIV (PLWH). New strategies are needed to reduce the burden of disease in PLWH; this is especially true in Florida, which maintains high incidence of HIV in the United States. As many studies have determined that there is an association between poor sleep quality and cognitive dysfunction in the general population, we seek to determine if this association also exists among PLWH. We performed a cross-sectional analysis using data collected by the Southern HIV and Alcohol Research Consortium (SHARC) during the Marijuana Associated Planning and Long-Term Effects (MAPLE) study. Our outcome of interest is cognitive impairment and our exposure of interest is sleep quality, as measured by survey items 4, 6, and 8 of the Pittsburgh Sleep Quality Index (PSQI). 265 participants were included in our final analysis. We found that sleeping between 5 and 6 hours per night was associated with 2.89 times increased odds of cognitive impairment (95% CI = 1.34-6.34). PSQI components 6 and 8 were not correlated to the outcome, so they were dropped along with other variables. Our results indicate that PLWH who slept 5 to 6 hours per night were more likely to be classified as cognitively impaired. Clinicians could use these results to modify the sleep health of PLWH who are at risk for developing cognitive impairment. Future research should investigate the possibility of a causal relationship between sleep and cognition in PLWH.


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Research Pitch

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